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High Purity Stable Hydroxypropyl Methylcellulose In Pharmaceutical Field
| MOQ: | 1000kg |
| Price: | ≥1000kg US$ 5.07 ≥5000kg US$ 4.52 |
| Standard Packaging: | 80×60×20cm Bagged or Barrelled |
| Delivery Period: | 5-8 work days |
| Payment Method: | L/C,D/A,D/P,T/T,Western Union,MoneyGram |
| Supply Capacity: | 200 T/Year |
High Quality Hydroxypropyl Methylcellulose
,Stable Hydroxypropyl Methylcellulose
Hydroxypropyl methylcellulose is mainly used as a pharmaceutical excipient in the pharmaceutical field. As a non-toxic and odorless polymer, HPMC is widely used in pharmaceutical formulations, serving functions such as thickening, film formation, binding, and controlled release. It is widely used in the preparation of formulations, including sustained-release agents, suspending agents, controlled-release agents, and stabilizers. It can also be used as a capsule shell material.
- As a binder and disintegrant in tablets: Its swelling coefficient after absorbing water can reach hundreds of times, significantly improving disintegration and dissolution release rates.For example, some studies have shown that replacing the original binder starch paste in ibuprofen formulations with HPMC can effectively improve the dissolution of poorly soluble s and improve tablet quality.
- HPMC can be used as a film coating material: HPMC is a widely used gastric-soluble coating material with good film-forming properties, forming films with suitable strength, transparent coating, and resistance to brittleness. The coating film is relatively stable under light, heat, and certain humidity conditions, and is soluble in organic solvents and water. It has little adverse effect on the disintegration and dissolution of tablets.
- HPMC as a capsule shell material: Currently, HPMC is also commonly used in the preparation of capsule shells. Compared with gelatin capsule shells, it has significant advantages. Firstly, it can overcome the cross-linking effect of gelatin, and secondly, its water content is much lower than that of gelatin.
- Appearance: White or off-white powder with no odor or slight odor, free of visible impurities
- Identification: Verified by TLC or UV spectroscopy
- Content Assay: Specific ratio of methyl and hydroxypropyl groups verified by GC or HPLC
- Moisture Content: Below 5% for storage stability
- pH: 6.0-8.0 for solution stability
- Viscosity: Specific range at 2% aqueous solution (25°C)
- Heavy Metal Content: ≤20 ppm (as lead)
- Impurity Testing: Strict controls for non-fibrous impurities and microbial limits
- Solubility: Rapid dissolution in cold water forming clear solution
- Cosmetics & Coatings: Water-based paints (Grade E15) for uniform film formation; shampoo/toothpaste (Grade E5) for suspension enhancement
- Food Industry: Dairy/sauce thickening (Food-Grade HPMC) as gelatin alternative in vegan products
| TEST ITEM | SPECIFICATION | TEST RESULT |
|---|---|---|
| APPEARANCE | WHITE POWDER OR GRANULES | WHITE POWDER OR GRANULES |
| IDENTIFICATION | CONFORM | CONFORM |
| METHOXYL CONTENT (wt%) | 19.0-24.0 | 21.4 |
| HYDROXYPROPYL CONTENT (wt%) | 4.0-12.0 | 8.4 |
| PH | 5.5-8.0 | 7.2 |
| LOSS ON DRYING (wt%) | 5.0 max | 3.6 |
| HEAVY METALS (ppm) | 20 max | <20 |
| ARSENIC (ppm) | 3 max | <3 |
| WATER INSOLUBLE MATTER % | 0.5 max | 0.1 |
| APPARENT VISCOSITY (cp) | 80000-130000 | 122078 |
| RESIDUE ON IGNITION (wt%) | 1.5 max | 1.4 |
| TOTAL BACTERIUM | 1000/gram max | 88 |
| MOLD | 100/gram max | 76 |
| ESCHERICHIA COLI | NEGATIVE | NOT DETECT |
A: Trading company.
A: Hydroxy Ethyl Cellulose (HEC), Ethyl Cellulose (EC), CMC-NH4, Chlorinated Polypropylene (CPP), N-Butyryl Chloride, HPMC, Red Base KD.
A: T/T (Telegraphic Transfer), L/C (Letter of Credit), D/A (Documents Against Acceptance), D/P (Documents Against Payment), or as per customer requirements.
A: Typically: 100% advance T/T payment, or 30% advance T/T payment with the balance against copy of B/L, or 100% L/C at sight.
A: Yes, we provide free samples (≤500g), but shipping costs are at the buyer's expense.
A: Usually 7-10 working days after payment.
A: We monitor the goods throughout the production-to-sales process and resolve any issues for our customers.
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